Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. Protect them from sunshine or rain. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Revision No. cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. Avicel PH-101. EMCOCEL XLM 90. Meet our leadership team. Biologicals by FMC. The product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. Formulators select it when they need to enhance a formulations robustness especially when less compactable diluents and binders are used. AFFINISOL hydroxypropyl methylcellulose (HPMC) is a water-soluble cellulosic polymer that can help optimize solubility enhancement of poorly soluble drugs by maintaining stable solid dispersions and inhibiting API crystallization. MATERIAL SAFETY DATA SHEET Avicel RC/CL Microcrystalline Cellulose and Sodium Carboxymethylcellulose MSDS Ref. Date Approved: 05/25/2010. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. }o]X4]. $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ? Although the breakup of cellulose to form colloidal microcrystalline cellulose has no impact on calorific content of the material, colloidal microcrystalline cellulose contain soluble components (hydrocolloids) that are introduced during processing, which add calories to the product. However, consumption of large quantities of the material may have a laxative effect. The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. Microcrystalline cellulose (MCC) for industrial purposes is usually obtained from wood pulp and purified cotton linters. Cellulose microcrystalline MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. EMCOCEL - JRS Pharma msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, : 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication It is insoluble in water, dilute acids, common organic solvents and oils, partially soluble with . B;vLZpHU%ChUyD+[ DC remains the most economical technique to produce large batches of tablets, however its efficacy is directly impacted by the raw material attributes. Microcrystalline cellulose is a commonly used excipient in the . Fmc | Sds >> Htn@sHaYoEJ*H[G&o)o9;0s N'3[*%M]vAu#9Tqpg9D& Product Specifications: Chemical and Physical: Loss on drying, % NMT 6.0* Viscosity, cps, 1.2% solids, 120 sec 39 to 91 . The United States Food and Drug Administration considers microcrystalline cellulose a safe material for all animal species. It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. Avicel RC-591 & CL-611 | IMCD US pfTr^i5wOg)y .6 68ZWN hZB{u7ps@uWm 2#@+o/Z {vd^qHe42)Xz[T|[6:q/ i0lGX*}L[7;SGS "lj@::4G[IN{ FMC Corporation: Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations DE102009022738A1 (de) * 2009-05-26: 2010-12-09: J. Rettenmaier & Shne Gmbh + Co. Kg . Product Name: Microcrystalline Cellulose 1.2. The formed cellulose molecules pack themselves closely to each other, stabilised through hydrogen bonds, creating crystalline regions interspersed with amorphous regions. q86@on$^X_HuH;3` Learn about FMC's industry leading goal of net-zero emissions by 2035. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. endobj MCC helps in the formation of spheres because of its . It works as a moisture sponge and permits the controlled growth of spheroids. Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. Product name: Microcrystalline cellulose; CBnumber: CB4217972; CAS: 9004-34-6; EINECS Number: 232-674-9; Synonyms: MICROCRYSTALLINE CELLULOSE,cellulose; Product and Company Identification . The product would later go on to be commercialized under the brand name Avicel by FMC Corporation. Your file is uploaded and ready to be published. (1962). !(!0*21/*.-4;K@48G9-.BYBGNPTUT3? : 5. Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. METHOCEL products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe. It is hygroscopic and insoluble in water. ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM "l%I-*j|-)@ EtG[TQd%8,.fg4QqH'-dV ?3Z#GK# dGnF7x*3yY\VUwPhmyYT@f67Zcsmdi!%94K@:L# vJeU-kzRT-(YX/fKC CAS #: 9004-34-6 1.6. Avicel co-processed grades are co-spray dried blends of Avicel microcrystalline cellulose with synergistic pharmaceutical excipients to yield functional benefits beyond simple physical blends. Microcrystalline Cellulose (MCC) Manufacturing Industry. Pharmacel 112 can be used in a wide range of oral solid dosage (OSD) forms as binder, compressing agent . Carboxymethyl Cellulose Sodium N/A Nutrition & Biosciences www.pharma.dupont.com HO 00017 - 0 E L 02.2020 www.dupontnutritionandbiosciences.com . Microcrystalline cellulose (MCC) is one of the most important tableting excipients thanks to its outstanding dry binding properties, enabling the manufacture of tablets by direct compression (DC). By producing Avicel . High performance lubricant that brings more to the tablet. ( Pharmacel 112 - Home - DFE Pharma Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) SDS - Safety Data Sheet. There is a secret ingredient in your burgers: wood pulp - Quartz SAFETY DATA SHEET - Fisher Sci /Contents 4 0 R No: 9004-34-6-5 Version: Global Date Approved: 10/16/1998 . Further elaborations can then be performed on the obtained material to produce many other grades of Microcrystalline cellulose. United Nations Sustainable Development Goals, Alginates Protanal, Manucol, Protacid and More, Barrier membrane, Controlled release hydrophilic matrix, Taste masking, Carrageenan Gelcarin, Viscarin and More, Controlled release hydrophilic matrix, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Rheology modifier, Rheology modifier/stabilizer, Binder, Controlled release hydrophilic matrix, Rheology modifier, Rheology modifier/stabilizer, Shell - hard capsule, Tablet coatings, Thin films, Topical, Capsules, Other, Solutions, Suspensions, Tablets, Controlled release hydrophilic matrix, Hot melt extrusion, Muco-adhesive, Osmotic pump, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Topical. Go to Investor Relations. This extends the funcionality of microcrystalline cellulose to meet specific viscosity, gelling, suspension and stabilizing properties ChemPoint is an approved supplier of LATTICE MCC in industrial applications, providing dedicated marketing, sales, order fulfillment, and technical support for customers in the EMEA region, Protect and improve AI potency, entrap oil droplets and improve stability, physical barrier that helps suspend particles and breaks down under shear and reforms quickly under rest. ES454445A1 - Procedimiento para preparar una crema lactica de buena con We are artists at heart and creators by nature. POLYOX resins are nonionic polyethylene oxide solubility polymers. Manufacturer: FMC BioPolymer. Home | FMC Corp 0.25 - 0.37. In many applications, one METHOCEL product can perform the job of two, three or even more ingredients saving money and time. Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm Alginate drug delivery harnesses the unique properties of seaweed for premier performance in multiple pharmaceutical and nutraceutical applications; they impart viscosity in solutions and even form a three-dimensional gel in the presence of calcium ions. Chemical Formula: (C6H10O5)n 1.4. Eur., JPE . They are soluble in a wide range of organic solvents, beginning with aliphatic alcohols such as ethanol and isopropanol, and are compatible with most other familiar organic solvent chemistries, including ether alcohols, ketones, aromatic hydrocarbons and many more. Avicel CL-611 Microcrystalline Cellulose and - FMC - YUMPU : CL-611NF Date Approved: 01/13/2010. They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. ). Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. Synergies to simplify formulation challenges and reduce operational costs. MATERIAL SAFETY DATA SHEET - Sevron CAS 9004-34-6, pH 5 - 7.5. In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. To meet their exacting standards, we deliver a wide choice of relevant solutions that are simultaneously replicable, scalable and high performing. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. gwf;J(e0o|1p{R~P^);ao!%{0KD7. /Producer(Sub Systems, Inc.)/CreationDate(D:20181207095625+05'00')/ModDate(D:20181207095625+05'00')/Creator(Sub Systems, Inc.) EP1551879A4 - Production of microcrystalline cellulose - Google This Microcrystalline Cellulose . Some substance identifiers may have been claimed confidential, or may . By utilizing proprietary co-processing technologies, Dupont also manufactures LATTICE NTC products. Heavy metals, % NMT 0.001 \C[i+rY2$V,,WT#_)3K?=/fW%[,lE"V?C PipEAz_xO;`cZsC0qcx;@tp]c*T7ge @Mty?]@SNmpf/]q#I,G1I?SR.@z*Xb KjR hb{T$CQrr Yx%O@~57eL5S\r-|EZ)Y.C]KuIlW]@12KY,S]C"e%b*|YX122igjl; @! ,}b;XQ})+l{~d_=sUtl V"CbKas+;fc>]bt#F,Md]]!5xae ;}rr^NI]rUc^,5Lc(fyyp*a=~U}WveuTLYX/ _V{#* g(*Rrm0gyv9i@0UT:A+{eW/y BS3_!Qv rt^BN! % Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Watch Now. << Microcrystalline cellulose: The inexhaustible treasure for Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. SUBSTANCE IDENTIFICATION 1.1. EINECS #: 232-674-9 1.7. MATERIAL SAFETY DATA SHEET Avicel PH Microcrystalline Cellulose MSDS Ref. Avicel Microcrystalline Cellulose is a safe and non-hazardous material that is widely used in pharmaceutical formulations and food products (as a bulking agent and to add crispness). q9;v80 Quantity: 1 700 kgs. PDF Safety Data Sheet - Accentuate Microcrystalline Cellulose (Mcc) Market Research Report 2023-2026