It bounced around .53 to .25 then .50 again but never above. A dosage change can start to be felt for me in 3 days and reaches fullness in about a week, but if it is too big a dosage change the symptoms can last for week(s) afterward till my body adjusts. Best, Rachel. That is a real challenge but I know one lady with both Graves and Hashi's who got treated by a Naturopath who was able to keep her thyroid levels normal with just the natural methods. Drug class: Antithyroid agents. Yes, Ive had doctors try to wean me off twice. Could you be swinging back into hyperthyroid? We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. Treatment and prognosis of Graves disease in children and adolescents. Methimazole is an antithyroid medicine. By using this Site you agree to the following, By using this Site you agree to the following. This was very irresponsible of them and I was not able to be well enough to work for a year after that. even my hair started falling out and to me to be a woman and have your hair fall out is the worst thing in the world. Mercado M, Mendoza-Zubieta V, Bautista-Osorio R, Espinoza-de los. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Thank you so much! I never was given clarity about what "the damage" entailed though:(. Some of the effects of skipping or stopping your thyroid medication are obvious, while others are so subtle they can go undiagnosed for years. I STOPPED TAKING mathemizol on may 11, 2017 after 3 years of being sick. Initial dose: Mild hyperthyroidism: 15 mg orally per day. It interferes with the step that causes the iodination of tyrosine residues in thyroglobulin, mediated by the enzyme thyroid peroxidase, thus preventing the synthesis of thyroxine (T4) and triiodothyronine (T3). I have hyper numbers - very low TSH and high/normal T4 and I have the same kind of symptoms you have: freezing cold and sometimes achy legs. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Can You Eat Soy If You Have a Thyroid Condition? I have had this for 2 years and I just got off the tapazole for at lease 6 weeks until the check my blood again. Diabetes Tests And Diagnosis: What To Expect During Your Medical And Physical Examinations? Version: 4.01. It got to the point where I could barely eat. Same as sudden weather changes, we get headaches etc. Medically reviewed by Drugs.com on Feb 20, 2023. Her vital signs are blood pressure of 184/106 mmHg, heart rate of 130 beats per minute, respiratory rate of 22 breaths per minute, and temperature of 102.7F. Should I stop Methimazole over a high TSH? over a year ago. Levels of hormone can swing up quickly. And other symptoms of hypothyroidism. She is the author of "The Thyroid Diet Revolution.". Methimazole is an antithyroid medicine. Debilitating fatigue; tiredness; pressure in head - related, Diagnosed with Graves' disease - my symptoms are high pulse, loose stools and very tired, Graves Disease - Hyperthyroid does anyone have the same symptoms. It is FREE! Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Hi, What was your heart rate when you were at the hospital on Saturday? Special Populations Untreated Graves' disease caused severe problems for me. Your blood may need to be tested often. You may report side effects to FDA at 1-800-FDA-1088. Management of severe thyrotoxicosis when the gastrointestinal tract is compromised. What many people don't realize is that there are quite a few symptoms that can apply to either/both hyper and hypo. Weaning off of Methimazole What next? Why Your Thyroid Hormone Levels May Be Fluctuating, Medications Used to Treat Thyroid Disease, Hyperthyroidism vs. Hypothyroidism: Differences and Symptoms, Thyroid Disease Facts and Statistics: What You Need to Know, Guide to Dietary Supplements and Thyroid Disease. Endocrinologic emergencies often fall at the wayside and are not generally considered as a possible diagnosis up front in patients in the emergency department who meet the criteria for systemic inflammatory response syndrome (SIRS). i teally feel I have late stage chronic lime. But the symptoms and side effects associated with thyroid disease can make it difficult to know whether you feel better overall with or without your thyroid medication. I'm on 2.5mg sun, we'd, Friday I was stressed about some things before. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. They told me to do that when I was taking 4 pills a day (20 mg) to get a test. Worsening of constipation or GI issues. Cold intolerance is a typical hypo symptom, but I've always had periods of heat intolerance as well and I've not been hyper in the past 12 yrs. If you are on a beta blocker for your heart rate (propranolol, atenolol, metoprolol, etc), your doctor may discontinue, decrease the dose, or keep the dose the same with plans to wean the medication in the weeks and . Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. I tapered and stopped completely and felt so good. appropriate medical assistance immediately. Gimel is right, it only has a 6 hour half life. While you may experience some symptoms of overactive thyroid more than others, and you may even consider some of them beneficial, it is important to be aware of the strain this condition is putting on your heart, bones, and overall health. Paying for medications can be stressful. I take individual vitamins and supps daily: B complex, C, D, LipoFlavinoid, potassium magnesium asparate, B2, CoQ10, (the last 3 for migraine) Flax capsules, Biotin. Some people have Graves alone, some have Hashi's alone and some people have both Graves and Hashi's at the same time. Serious and sometimes fatal infections may occur during treatment with methimazole. If there is a contraindication for the use of methimazole, alternative methods to treat hyperthyroidism should be considered after discharge, such as radioactive iodine or surgery. Found that I could not take vitamin D pills, that they had to be the gel caps. Dosage form: oral tablet (10 mg; 5 mg) Use methimazole regularly to get the most benefit, even if you feel fine or have no symptoms of hyperthyroidism. Get your TBII or TRAb antibodies tested for Graves, anti-TPO and TGAb for hashimoto's. Your phone, computer, or another alarm can be programmed to give you a daily reminder. Shaky? Im feeling exactly those symptoms minus the weight loss because that hasnt changed on 2.5. And then see if you need the beta blocker if what you're experiencing is heart palpitations/shakiness. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. I refused to take blood pressure the whole time. I was tested again today my gp ordered that I do will have results later today. I got pulled over for speeding on Christmas eve last year. No chance of a beach here. I'd never stop any medication cold turkey. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Most people who have thyroid disease feel better with the appropriate medication. STIs are the most common cause of genital sores. The anxiety and the eye problem could be symptoms of Hyperthyroid, or it might be unrelated. Anthing would be helpful. But I was stressing about some dumb things before. PMID: 24176474. I told my endo. Diagnosis of thyroid storm can be somewhat of a challenge because of this, but a scoring system developed by Burch and Wartofsky 1 can assist in determining the likelihood of thyroid storm in patients based on presenting signs and symptoms. My doctor took me completely off Methimazole at 1 year with very poor resultsI was off the charts in 2 1/2 weeks and back up to 20MG a day to get me stable. Do not use methimazole in larger or smaller amounts or for longer than recommended. The third type of carnitine is Proprionyl-L-Carnitine recommended for heart disease. upper right abdominal pain. Herpes spreads by oral, vaginal and anal sex. Not all possible interactions are listed in this medication guide. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. I have not been on it for 6 days now. HELP. It can also increase the risk of developing a dangerous condition known asthyroid storm, which has a high fatality rate. The question is now . Skip the missed dose if it is almost time for your next scheduled dose. Tell your doctor if you are pregnant or if you become pregnant while using this medicine. Sounds like your doctor wants to work with you though if he gave you that choice. His goal is to wean me off very slowly. I want to know if I should see another doctor. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. My Endocrinologist has started weaning me off of Methimazole. Nabil N, Miner D, Amatruda J. Methimazole: an alternative route of administration. However, since starting to wean off, my numbers have gotten closer to the Hyper T side again. Seemed like it got stuck or something. Do not give this medicine to a child without medical advice. This required my Endo to make a lot of lowering adjustments and I adjusted my carnitine dosages. (PTU), Methimazole, or Tapazole thyroid medicine 4 days before their tests. pale skin, easy bruising, unusual bleeding. Usual Pediatric Dose for Hyperthyroidism: Initial dose: 0.4 mg/kg orally per dayMaintenance dose: 0.2 mg/kg orally per day (approximately half the initial dose) Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals. I am weaning off methimazole i was only taking 10 mg a day down to 7.5 mg for 2 weeks feeling lightheaded and was wondering if anyone knew of any side effects? Again, be sure to discuss any concerns with your doctor and do not stop taking your medication without consulting with them first. Because I thought they might be responsible for lowering TSH. If you are not taking your thyroid medication because of one or more of the following reasons, try the suggested solutions to address your concerns. Bridge to EM: Senior Medical Student Curriculum, GroundED in EM: A Third-Year Student Curriculum. Methimazole side effects. If you skip or stop your medicine entirely, you can experience a number of short-term and long-term consequences, including: Untreated hyperthyroidism can increase your risk of stroke or heart attack. How should this medicine be used? I'm afraid the L Carnitine I'll make me have more symptoms. Typical dosing for methimazole The dose of methimazole for adults ranges from 5 to 40 mg by mouth per day depending on how severe your hyperthyroidism is. They are still really active so she changed her mind and I am staying on the medication. Even while I was having a thyroid storm and my hr was way to high it took the doctor telling me I was going to die before I let him give me meds to slow my heart. Hyperthyroidism can cause unwanted symptoms like anxiety and excessive sweating. You have a 54-year-old female who presents to the emergency department with a chief complaint of just feeling out of it. She has felt off and on for the past 12 hours and has had an occasional cough with some sputum production along with the shakes and chills. She also feels as if her heart was going at a mile a minute and because of this, she is very much out of breath. Endometriosis And Thyroid disease: Is There Really A Connection? I agree, doctor should have told you this. But have plenty of lab slips on hand and get checked if you feel like hurting someone. Some my symptoms inc My thyroid was stable for about 4 years, then suddenly, after my Mom's death, my thyroid went into hypothyroid. I was on 10mg (5mg x 2)a day Carbimazole. Press J to jump to the feed. Saturday evening, I took my blood pressure, and the systolic reading was over 200. Are you losing weight? Dizziness. Other than that, he said that they didn't find anything, such as pneumonia. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. I am at 15 MG per weekI take 5 mg on M/W/F and my body is getting used to it but I have passed the two year mark and no signs of it abating. Endocrine causes of dangerous Fever. To become an empowered patient, you need to obtain a copy of any medical documentation done on you, either lab tests or reports from other physicians and keep your own file so you can see your progresss. I don't believe our bodies respond well to abrupt changes. We offer this Site AS IS and without any warranties. "Long-term, low-dose methimazole treatment for 60-120 months is a safe and effective treatment for Graves hyperthyroidism and is accompanied by much higher remission rates than the usual 18-24 months of methimazole treatment," he summarized. And I am still could thins be a side affect of relapse or not taking my meds? So this is a surprise to me that I migh have Graves or toxic nodules as I feel I'm bouncing back with no symptoms of hyper. I think it's common to wean off after being in normal range for 12-18 months to see if it's gone into remission, that's what my endocrinologist did the first time my graves was diagnosed. Have been on it for 18 months. Being short tempered can go along with being fatigued and/or depressed or not feeling well in general. I'm not on meds yet but I agree with AnnLW. Yes I know it's dumb and it's something I struggle with daily. Unfortunately, there isn't a natural or herbal replacement for thyroid hormone. I am a 52 year old female and I had been on 15MG Methimazole for the over 2 months and Endo lower the dosage to 10MG when my Triio Hi, I'm not in hypo yet I don't think the doctors just think that I'm going into hypo..? I just watched my diet, no red meat, no sugar, no wheat or dairy, and room temp water. I had to do the same for 2 weeks and had no withdrawal symptoms and I was on 30mg at the time. Its been almost a month now on the 2.5 so Im going to get the blood work rechecked within a week or so. I hope you go into remission and you dont have to keep taking those god forsaken meds. Center for Hormonal Health and Well-Being, Low body temperature;constantly feeling cold, Weight gain; inability to lose weight despite diet and exercise, Infertility, miscarriage, stillbirth, or premature labor, Dramatically increased appetite and thirst. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. JayValle, I don't remember your thyroid history whether you have Hashimoto's and you started off hyper? I was on 5 mg once a day. My levels are going into the hypo range and so my gp told me to stop taking methimazole. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. with 87 to 100 percent becoming euthyroid within a few weeks to a few months . Hair loss. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Couldn't go outside all summer. brain fog, loss memeory, Phantom touch Help me please, unemployed, GA medicaid. You will be able to stop your methimazole or PTU immediately. They do better controlling their thyroid hormones using Regular L-Carnitine. Have been able to come off of the beta blocker as my blood pressure and heart rate have dropped back to a low/low normal range. Methimazole prevents the thyroid gland from producing too much thyroid hormone. Methimazole can pass into breast milk and may harm a nursing baby. A list of national and international resources and hotlines to help connect you to needed health and medical services. HI, I was diagnosed with Graves Disease last fall (2016). Stop using methimazole and call your doctor right away if you have signs of infection such as: There are 3 kinds of L Carnitine suppslements what kind did you take to help? Could the anxiety be stemming from you actually still needing the methimazole? A list of national and international resources and hotlines to help connect you to needed health and medical services. They took blood work and X-rays, and this went on for over 4 hours. The problem can be changing your diet, as you don't know how the thyroid will react to this. Some people get thyroiditis due to viral illnesses but it is usually short lived, like a couple of months at most. Your hair loss or hair thinning may also be a symptom of hyperthyroidism, when your thyroid gland is overactive and makes too much thyroid hormone. At my last visit, my Dr suggested seeing if I could wean off my medicine. Helpful - 0 Comment leilajax Gimel is right, it only has a 6 hour half life. Ive been on the 5 mg daily for a few years now. For myself, I found that I could not lower my dose too quickly or stop my Methimazole altogether. The article suggested hyperthyroid patients and patients who have thyroid storm benefit from taking 3,000 mg of Regular L-Carnitine. Her overall presentation does not seem to add up in being secondary to urosepsis. It flared up my GERD do now taking Prevacid and going to go to the counselor.. unusual tiredness or weakness. Create an account to follow your favorite communities and start taking part in conversations. Growth of thyroid nodules, increasing goiter size. I was taking a dosage of forty, then cut it down to twenty for about two weeks, and then was taken off of it entirely. Methimazole doses are based on weight in children, and any changes may affect your child's dose. If you are hypothyroidwhether due to Hashimoto's, Graves' disease treatment, thyroid surgery, or congenital hypothyroidismfailing to take your thyroid hormone replacement medication can pose many risks to your health. Egton Medical Information Systems Limited. I did this (decided to lessen the dose) all by myself with a naturopath's advice (my "specialist" seems to have forgotten about me and never did the follow up in mid-March, and I am not disappointed =;) The biggest help has been to deal with my stress. Get your prescription refilled before you run out of medicine completely. She seems relatively anxious on physical exam, and you note that she is diaphoretic. Swollen hands, feet, and face. first cutting the 5mg tablet in half then in 1/4's. Now down to 5 mg a day, 6 days a week (so 30 mg a week). Natural Endocrine Solutions. https://patient.info/forums/discuss/stopping-methimazole-543742. Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): Change in taste. Additional benefit of PTU in thyroid storm: Inhibition of the peripheral conversion of T4 to T3 (3rdB), PTU and MMI can both be administered through the rectal route as a suppository and retention enema, Shown to have good response in several trials, Intravenous (IV) thionamides are currently not commercially available in the United States, IV formulation of MMI is available in Europe, Success reported in case reports and case series of treating thyroid storm with IV MMI compounded formulations, PTU: black box warning for severe and/or life-threatening hepatotoxicity issued by FDA in 2010, Tends to be dose-related with MMI, unlike PTU, Granulocyte colony-stimulating factors (G-CSFs) can be used in the management of thionamide-induced agranulocytosis, Used to prevent the release of pre-formed thyroid hormone from the thyroid gland, Administration of inorganic iodine should be delayed for at least one hour after initiation of thionamide therapy, Iodine load can serve as a substrate for thyroid hormone synthesis and exacerbate thyroid storm, Iodine content of formations (NOTE: Solutions, Dissolve the dose in solution of 3 to 4 ounces of milk, fruit juice, or water to ensure that the full dose is given and to mask the bitter taste. Talk to your doctor about these issues, as they can be the effects of your thyroid hormone levels getting back to normal. Unusual weakness or fatigue, fever, headache, skin rash, muscle or joint pain, loss of appetite, pain, tingling, or numbness in the hands or feet. The ENT in the group did suppression therapy. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Be sure to check with your doctor before you stop taking these medicines. Got dosage down to 5mgs. When starting medication, your appetite may change, you may be feeling tired, or you could have a change in your bowel movements. Having irrational thoughts worries. Verywell Health's content is for informational and educational purposes only. When I was in the ER, they hooked me up to the BP cuff, and it stayed there, turning off and on the entire time. However, since starting to wean off, my numbers have gotten closer to the Hyper T side again. So I don't think there is one size fits all but I do believe you need the information from the tests your doc does as well as learning about your body and its symptoms and what works and what doesn't in order to get well. A dosage change can start to be felt for me in 3 days and reaches fullness in about a week, but if it is too big a dosage change the symptoms can last for week (s) afterward till my body adjusts. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. I am so overwhelmed and only end up having a few days out of a month. I feel fine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It seems to me that I still am feeling more hyper, with some new symptoms, the worst being the high blood pressure, and the "gassiness". Sometimes it can take a few months to adjust your medication, but the end result is well worth it. Herpes spreads by oral, vaginal and anal sex. Tell your doctor about all your current medicines and any you start or stop using, especially: a blood thinner--warfarin, Coumadin, Jantoven; or. If the hyperthyroidism returns, the antithyroid drugs are re-started. When did you start going off it? If you lack thyroid hormone for a long period of time, you face the risk of a very dangerous condition called myxedema coma, which can ultimately be fatal. You may need a different medication or a dose adjustment, but you should never quit your medication without your doctor's approval. Methimazole may cause serious side effects. However I choice to go off the med and now I'm wondering what the side effects may be because of my choice. Reddit and its partners use cookies and similar technologies to provide you with a better experience. My T3 and T4 are at mid to lower end of the range. Are these symtpoms of both hyper and hypo? ACMT Toxicology Visual Pearl: Swollen Lips, PECARN Pediatric Head Trauma: Official Visual Decision Aid, A Starters Roadmap to EM Resources: Books, Websites, and Apps, D50 vs D10 for Severe Hypoglycemia in the Emergency Department, The Dirty Epi Drip: IV Epinephrine When You Need It, Tips for Interpreting the CSF Opening Pressure, Trick of the Trade: Mix Ceftriaxone IM with Lidocaine for Less Pain, Trick of the Trade: Urine Pregnancy Test Without Urine, Wellness and Resiliency during Residency: EM is a career with unresolved stories, Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License, Academic Life in Emergency Medicine - All Rights Reserved (except for the PV Cards and MEdIC Series PDFs), Block the production and release of thyroid hormone (preventing the opposing team from getting the ball and scoring), Block the sympathetic outflow (preventing the soccer ball from going out of bounds), Block peripheral conversion of T4 to T3 (preventing penalty kicks), Mechanism of action: Inhibit thyroid peroxidase, an enzyme involved in the production of T3 and T4 through the iodination of tyrosine residues on thyroglobulin, Agents: propylthiouriacil (PTU) and methimazole (MMI), No head-to-head trials have shown any benefit of using one thionamide over another in the management of thyroid storm.